Ashwagandha (Withania somnifera) is a revered herb in Ayurvedic medicine, traditionally used for centuries to manage stress, boost immunity, and improve overall health. While generally considered safe for most people, ashwagandha root supplements can cause side effects, especially with high doses or prolonged use. Understanding these potential drawbacks is crucial before incorporating it into your wellness routine.
Common Side Effects
- Digestive Issues: The most frequently reported side effects involve the digestive system. These include nausea, vomiting, diarrhea, and stomach upset. Starting with a low dose and gradually increasing it can minimize these effects.
- Drowsiness & Sedation: Ashwagandha has calming properties. While beneficial for sleep, it can cause excessive drowsiness, particularly at higher doses. Avoid operating heavy machinery or driving if you experience this.
- Lowered Blood Sugar: Ashwagandha may lower blood sugar levels. Individuals with diabetes or hypoglycemia should monitor their blood glucose closely and consult their doctor before use.
- Lowered Blood Pressure: Similar to blood sugar, ashwagandha can reduce blood pressure. Those with hypotension or taking blood pressure medication should exercise caution.
Less Common, But Serious Side Effects
- Thyroid Issues: Ashwagandha can stimulate thyroid hormone production. Individuals with hyperthyroidism (overactive thyroid) should avoid ashwagandha. Those with hypothyroidism (underactive thyroid) should use it only under strict medical supervision, as it could potentially interfere with thyroid medication.
- Autoimmune Diseases: Because ashwagandha boosts the immune system, it may worsen symptoms in people with autoimmune diseases like rheumatoid arthritis, lupus, or multiple sclerosis.
- Liver Problems: Rare cases of liver damage have been linked to ashwagandha use. Discontinue use and seek medical attention if you experience symptoms like jaundice (yellowing of the skin or eyes), dark urine, or abdominal pain.
Who Should Avoid Ashwagandha?
- Pregnant and Breastfeeding Women: There isn’t enough reliable information to determine the safety of ashwagandha during pregnancy or breastfeeding. It’s best to avoid it.
- People with Thyroid Disorders: As mentioned above, caution is vital.
- Individuals with Autoimmune Diseases: Potential for symptom exacerbation.
- Those Scheduled for Surgery: Ashwagandha’s sedative effects may interact with anesthesia. Stop taking it at least two weeks before surgery.
Drug Interactions
Ashwagandha can interact with several medications, including:
- Immunosuppressants: May reduce their effectiveness.
- Sedatives: Can enhance their effects, leading to excessive drowsiness.
- Diabetes Medications: May cause blood sugar to drop too low.
- Blood Pressure Medications: May cause blood pressure to drop too low.
- Thyroid Medications: May interfere with their function.


